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Actos

The Actos injury case attorneys at the Drug Law Center have assisted many victims who have suffered injuries by diabetic treatment medications.

Introduction

Actos Drug RecallThe anti-diabetic prescription drug Actos (pioglitazone) has been shown to be highly effective at controlling high blood sugar levels in individual suffering with Type II diabetes when used along with an effective exercise program and a proper diet. The FDA-approved thiazolidinedione-class drug is similar to Avandia (rosiglitazone) in the treatment of type II diabetes. However, when used alone or concomitantly with antidiabetic agents is known to worsen or cause CHF (congenital heart failure). The drug manufacturer has issued a black box warning that revealed the potential increase risks of developing bladder cancer.

The History of Actos

In 1999, the Food and Drug Administration approved Actos as a prescription only medication for treating type II diabetes. The initial signs of the potential risk of developing congenital heart failure when taking medication first became apparent in 2002. As a result, the FDA required that the drug maker updates their information to include heart failure risks associated with Actos use.

By 2007, Actos manufacturer Takeda Pharmaceuticals followed the FDA mandate to add Actos heart failure risks to its Black Box Warning Label. Three years later in 2010, the FDA announced it was launching an investigation into the safety and efficacy of Actos because data from a decade-long epidemiological study conducted by the drug maker revealed the potential risks of developing bladder cancer.

In June 2011, French regulators announced Actos sales would be discontinued in France. This was followed one month later (July 2011) when Takeda Pharmaceuticals voluntarily recalled Actos from the French medical marketplace.

In September 2011, Louisiana became the first state to formulate an Actos class-action lawsuit against Takeda Pharmaceuticals. By December that same year, Louisiana federal court consolidates their Actos lawsuits into a multidistrict litigation (MDL) case. Even though many of the study results were conclusive, the drug manufacturer continued to deny the dangers involved in taking Actos and the correlation of an increasing risk of developing bladder cancer in congestive heart failure.

Actos Side Effects

Actos is designed to increase sensitivity to the body’s insulin levels. The medication is used specifically to treat Type II diabetes and not diabetic ketoacidosis or type I diabetes generic forms of Actos are yet to become available in America but is sold as pioglitazone in other countries. Serious to severe side effects from taking Actos include:

  • Hypoglycemia (low blood sugar)
  • Vision loss
  • Vision changes including blurred vision
  • Vomiting and nausea
  • Jaundice caused by hepatic effects

The most common mild side effects associated with the use of taking Actos include:

  • Mouth pain
  • Tooth problems
  • Muscle or back pain
  • Weight gain
  • Headaches
  • Flu/cold-like symptoms including a sore throat, coughing, sneezing, and stuffy nose

Even though research is not conclusive on probable cause, many patients taking Actos have suffered hepatic effects, including both fatal and non-fatal failures.

Actos Contraindications

Before patients are prescribed Actos as an effective type II diabetes to control high blood sugar levels, the doctor will usually take a comprehensive medical history. This is because certain patients should never take Actos because of contraindications if they suffer from:

  • Bladder cancer
  • Broken bones
  • Infections
  • Low blood sugar
  • Abnormal liver function (found through testing)
  • Visible and not visible water retention
  • Liver problems
  • Severe heart failure
  • Chronic heart failure
  • Macular edema (swelling of the macula)
  • Any serious symptom of heart failure
  • Fever
  • Recent surgical procedure

Actos Recall

While both Germany and France have recalled Takeda Pharmaceuticals’ anti-diabetic medication Actos, the US Food and Administration has yet to pull the drug from the medical marketplace. Even so, the FDA has been closely monitoring many of the comprehensive ongoing research and study programs to determine if the drug causes more than just heart failure, bladder cancer, and other serious conditions.

Actos Lawsuits

Many patients have taken the diabetic medication Actos since the U.S. Food and Drug Administration first approved the medication nearly two decades ago. Some patients have developed bladder cancer and are likely entitled to receive monetary compensation from Takeda Pharmaceuticals by filing and resolving an Actos lawsuit.

  • $3 Million Verdict Awarded to a Pennsylvania Man in Actos Lawsuit

March 2015 – Because a jury reached a verdict in an Actos lawsuit, pharmaceutical giant Takeda Pharmaceuticals will have to pay out more than $3 million for permanent injuries caused by the plaintiff after taking the anti-diabetes medication. During the trial, the plaintiff claimed he developed life-threatening bladder cancer after years of taking the Type IIdiabetes treatment drug.

The jury in the case reviewed evidence and heard testimony surrounding Actos side effects and found that the pharmaceutical drug maker acted recklessly and had indifference toward the plaintiff. As a result, the plaintiff was awarded over $1.3 million in punitive damages and $2.3 million in compensatory damages for his injuries.

The plaintiff was prescribed the diabetic treatment medication to control his blood sugar levels. Doctors claim that Actos is typically an alternative drug choice and is usually only prescribed when other anti-diabetes treatments have no effect. Even though the plaintiff had been taking the prescription medication since the end of 2008, he was not diagnosed with bladder cancer until nearly 30 months later in June 2011.

The jury awarded the punitive damages because of the indifference shown to the plaintiff by attorneys representing Takeda who claimed it was the plaintiff’s other health complications that were the direct result of developing bladder cancer. However, during the trial, the pharmaceutical company acknowledged the correlation between bladder cancer and Actos but acknowledged that there is yet to be a proven link.

  • Wrongful Death Lawsuit Involving Bladder Cancer Linked to Actos Use

June 2012 – Surviving family members of a loved one who took Actos for eight years have filed an Actos wrongful death lawsuit against the drug maker Takeda Pharmaceuticals after the man developed and died from bladder cancer. The plaintiffs claim that the death was associated with years of taking Actos to treat his diabetic condition.

Lawsuit documents filed in Cook County, Illinois claims it their loved one began taking Actos in 2000 and it was prescribed by his physician to treat type II diabetes. After approximately eight years, the patient was diagnosed with bladder tumors that were allegedly caused by Actos side effect. The next year, the man succumbed to his disease. The plaintiffs claim that it was not until two years later that the Food and Drug Administration issued a warning that showed a correlation with taking Actos in the development of bladder cancer.

  • Many Actos Bladder Cancer Lawsuits Have Been Filed by Grieving Families

March 2015 – Numerous Actos bladder cancer lawsuits have been filed by a group of plaintiffs alleging that the drug maker Takeda Pharmaceuticals failed to warn of the drug’s serious side effects. The plaintiffs in these cases are alleging that the damages they endure where the result of taking the diabetic medication for years. A wrongful death claims filed by a Texas plaintiff whose husband took Actos for three years before dying of bladder cancer. A separate Florida plaintiff has filed a lawsuit against Takeda Pharmaceuticals when a loved one died of bladder cancer in 2006 after taking prescribed Actos for two years.

Takeda Pharmaceuticals is facing a wrongful death lawsuit filed by a California plaintiff claiming that her husband succumbed to bladder cancer in 2013 after taking the prescription Actos between 2004 and 2007. Another California plaintiff filed a wrongful death lawsuit claiming that her husband died from bladder cancer in 2014 after taking the medication between 2008 and 2011. Additionally, a Virginia plaintiff has filed a Takeda Pharmaceuticals Actos wrongful death lawsuit after her husband succumbed to bladder cancer in 2011 after taking Actos between 2007 and 2011.

  • Spouse Claims Loss of Consortium in an Actos Bladder Cancer Lawsuit

June 2012 – Takeda Pharmaceuticals is facing a mounting list of Actos bladder cancer lawsuits. This includes one filed by a married couple in Los Angeles after the wife developed bladder cancer from taking the anti-diabetes medicine starting some five years previously. The plaintiffs chose not to participate in the MDL (multidistrict litigation) case and instead is being heard individually in a Los Angeles courthouse.

Both plaintiffs are claiming that the drug manufacturer failed to adequately and appropriately warn them of using Actos and did not warn their prescribing physician of the serious side effects the drug can produce. This includes bladder cancer, congestive heart failure and at times death. Even though the wife developed bladder cancer in 2012, one year after the U.S. Food and Drug Administration issued a warning of serious potential side effects, she had been taking the medication for more than five years.

  • Another Actos Bladder Cancer Lawsuit Filed against Takeda Pharmaceuticals

March 2015 – Plaintiffs in New York have filed an Actos bladder cancer lawsuit against Takeda Pharmaceuticals alleging the medication cause his bladder cancer. The plaintiff claims that he began taking the prescription medication in 2007 to treat his Type II diabetes and was diagnosed with bladder cancer four years later in 2011. The plaintiff alleges that the serious side effects, the development of bladder cancer, and the need for surgery to treat his condition have caused extreme pain and suffering.

The plaintiff is claiming that had he known about the severe side effects that Actos can cause, he would not have taken the medication would have chosen a different option treatment. Even though this plaintiff’s case is treatable, he will require ongoing monitoring and additional medical care for the remainder of his life.

We Represent Actos Injury Victims

The Actos injury case attorneys at the Drug Law Center file and resolve Actos lawsuits on behalf of individuals who have suffered serious side effects, bladder cancer, and congestive heart failure after taking the anti-diabetes medication. We protect the rights of our clients and assist them in obtaining the financial compensation their family deserves.

If you have suffered a serious injury or lost a loved one after they took Actos, you are likely entitled to receive monetary compensation from a lawsuit or financial claim against Takeda Pharmaceuticals. Our team of dedicated personal injury attorneys specializes in wrongful death cases, medical malpractice claims, and product liability lawsuits. We build our cases to ensure our clients receive compensation for all of their damages including lost wages, medical expenses, pain, suffering and emotional distress.

Surviving family members of a loved one lost to Actos use are likely entitled to file a wrongful death lawsuit. In addition to obtaining financial recompense, families can hold the drug maker, for their negligence, failing to warn and selling a defective product.

We urge you to contact us today to schedule a comprehensive, no-obligation consultation at no charge to you. We are currently accepting Actos injury lawsuits through contingency fee agreements. This means we postpone payment of our legal services through a “no win/no fee” guarantee only after we successfully resolve your case through a negotiated out of court settlement or through a jury trial award.

Sources:
https://www.fda.gov/Drugs/DrugSafety/ucm259150.htm
http://www.mayoclinic.org/drugs-supplements/pioglitazone-oral-route/description/drg-20065503
https://www.fda.gov/Drugs/DrugSafety/ucm109136.htm
http://www.mayoclinic.org/diseases-conditions/diabetes/expert-answers/avandia/faq-20057996