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Cipro

The Cipro injury case attorneys at the Drug Law Center are currently evaluating and accepting new cases involving patients who suffered harm or wrongful death after taking the popular antibiotic medication.

Introduction

Cipro Drug RecallCipro (ciprofloxacin) is a popular antibiotic medication that is used to treat bacterial infections. The fluoroquinolone drug is also used to treat individuals exposed to the plague or anthrax. The medication is affected because it stops the growth of bacteria. The medicine is sold under its brand name Cipro and generic name ciprofloxacin. However, the drug can cause serious side effects including nausea, depression, diarrhea, or hallucinations. In addition, the FDA has warned users and doctors that Cipro and its generic medication ciprofloxacin might rupture tendons.

The History of Cipro

After Bayer, Inc scientists first synthesize the broad-spectrum antibiotic in 1981, it was found to inhibit cell division, thereby stopping the infection from growing. In 1987, the Food and Drug Administration (FDA) approved Cipro as the first oral broad-spectrum antibiotic in the fluoroquinolone class of drugs. The safety profile for the drug has been studied extensively and published in more than 32,000 publications. The FDA approved multiple uses for the drug including treatment for:

  • Urinary tract infections
  • Cystitis, urethritis, and kidney infections
  • Acute cystitis
  • Lower respiratory infection including tracheobronchitis, bronchitis, and pneumonia
  • Skin infections
  • Acute sinusitis
  • Infectious diarrhea including campylobacter infection, shigellosis, and E. coli (Escherichia coli infection)
  • Uncomplicated urethral and cervical gonorrhea STDs (sexually transmitted diseases)
  • Enteric fever (typhoid fever)
  • Inhaled anthrax
  • Complicated urinary tract infection in children (17 years and younger)

Who Should Avoid Taking Cipro?

While Cipro has enormous benefits for individuals suffering certain bacterial infections, patients with a history of hypersensitivity to the active ingredients and components of ciprofloxacin should avoid taking the medication. This includes antibacterial drugs from the quinolone class of medications. This is because these medications have been associated with potentially irreversible severe adverse reactions and disabling side effects that include:

  • Ruptured tendons
  • Tendinitis
  • Central nervous system effects
  • Peripheral neuropathy

It is important to check with your doctor if you are suffering from any of the conditions listed below to discuss whether you should take Cipro (ciprofloxacin). These include:

  • Clostridium difficile infection
  • Heart transplant
  • Lung transplant
  • Kidney transplant
  • Kidney impairment
  • G6PD deficiency (Glucose-6-phosphate dehydrogenase deficiency)
  • Q-T prolongation
  • Low seizure threshold
  • Kidney transplant
  • Tendon inflammation
  • Ruptured tendon
  • Very rapid heartbeat
  • Numbness
  • Low bloodstream potassium levels
  • Low bloodstream magnesium levels
  • Pseudo tumor celebri
  • Detached retina
  • Slow heart beat
  • Elevated pressure in the skull

Doctors often prescribe Cipro (ciprofloxacin) when all other antibiotics have proven to be ineffective when treating acute sinusitis, acute uncomplicated cystitis, and acute exacerbation of chronic bronchitis.

Certain medications negatively interact with Cipro and should not be taken concomitantly with the antibiotic. These include cisapride, tizanidine, terfenadine, and droperidol. Common medicines and substances that interact with Cipro include antacids, contraceptive medications, caffeine, multivitamins, ibuprofen, naproxen, diabetes medicines, didanosine buffered powder or tablets, cyclosporine warfarin, theophylline, sucralfate, and probenecid.

Patients must discuss side effects Cipro (ciprofloxacin) with their doctors if they have or have had any one of the following conditions including:

  • Clostridium difficile infection
  • Heart, lung, or kidney transplant
  • Ruptured tendon
  • Inflamed tendon
  • Congenital Q-T changes
  • Detached retina
  • Numbness
  • Pain or tingling sensation in the feeder hands
  • Low bloodstream magnesium or potassium levels
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • Seizures
  • Torsades de Pointes (very rapid heartbeat)
  • Low seizure threshold
  • A severe reaction to fluoroquinolone class of medications

Cipro Side Effects

Like most antibiotics, Cipro (ciprofloxacin) has mild to serious side effects that may affect the health and well-being of the patient while taking the medication and after. Mild Cipro side effects include:

  • Dizziness
  • Pounding heartbeat
  • Fast heart rate
  • Fainting
  • Anxiety
  • Stomach upset or pain
  • Popping sound
  • Snapping sound
  • Sudden Pain
  • Blurry Vision
  • Stiffness
  • Agitation
  • Muscle tenderness
  • Swollen muscles
  • Bruising
  • Confusion
  • Bloody or watery diarrhea
  • Hallucinations
  • Insomnia including sleeping issues or nightmares
  • Some form of loss of joint movement

Serious Cipro side effects include:

  • Unsteadiness or clumsiness
  • Breathing problems
  • Allergic reaction including swelling of the tongue, lips or face, eyes, itching, or skin rash
  • Feeling lightheaded
  • Difficulty passing urine
  • Irregular heartbeat
  • Seizures
  • Loosening, peeling, blistering or redness of the skin
  • Persistent headaches

Benefits vs. Permanent Side Effects

In May 2016, the Food and Drug Administration (FDA) informed the public that it required drug manufacturers to place stronger warnings and more information in the Black box warning label concerning fluoroquinolone class medications including Cipro, Levaquin, and Avelox. More than 26 million patients in the United States take these three brand-name medications or their generic version every year.

In the release of the Drug Safety Communication, the FDA wrote that they are “advising that the serious side effects associated with fluoroquinolone antibacterial drugs generally outweighed the benefits for patients with sinusitis, bronchitis, and uncomplicated urinary tract infections who have other treatment options.” The communication went on to say that “for patients with these conditions, fluoroquinolones, should be reserved for those who do not have an alternative treatment option.”

This new addition to the Black Box Warning label comes after nearly eight years after the FDA advisory committee required that the drug manufacturer inform the public back in 2008 that taking these drugs could cause tendinitis and tendon rupture. By 2013, the FDA was claiming that these medications could potentially cause peripheral neuropathy (permanent nerve damage).

The FDA hopes that informing the public, doctors, patients, and the entire medical community that users will make a more informed decision before taking the medication. The advice that the antibiotic could cause potentially permanent damage to joint, tendons, muscles and nerves and the body central nervous system could make potential users reconsider what to do and instead take other antibiotic drugs available and the medical marketplace that has less potential serious side effects. The FDA is trusting the doctors will be discouraged from prescribing fluoroquinolone medications when other treatments are available.

Cipro and Aortic Bulges and Tears

A warning from the U.S. Food and Drug Administration has alerted users of quinolone drugs including Cipro (ciprofloxacin) that the drug could cause nerve and tendon damage. This information was released after new research studies had surfaced that correlated potentially fatal medical conditions to taking Cipro, Levaquin, Avelox and their generic counterparts. The FDA warns that these drugs could cause bulges (aneurysms) and tears (aortic dissection) during and after short-term or long-term use.

In 2015, published studies analyzed the effects of fluoroquinolones and their ability to cause severe permanent tendon damage. The researchers hypothesized that the antibiotic properties of these medications had the ability to break down the body’s collagen, which is why it affected the lining of the aorta that is made up primarily of collagen. The 2015 JAMA Medical Journal publication made the correlation between fluoroquinolones in the increased potential risk of developing aneurysms or dissections after only two months of taking the drug.

One researcher in the study said that “reducing unnecessary fluoroquinolone treatments and prolonged treatment courses might have possibly prevented more than 200 aortic aneurysms in [the study’s] population.

Even though the Food and Drug Administration was placing new requirements on drug manufacturers issuing new warnings about the serious side effects of taking fluoroquinolones including Cipro (ciprofloxacin), Bayer, Inc., Johnson & Johnson, and its subsidiary Janssen Pharmaceuticals have reaffirmed the benefits of the drug stating that:

“At Janssen, our first priority is the well-being of the people who use our medicines. We are reviewing the Drug Safety Communication and will continue our ongoing collaboration with the FDA to support the safe and appropriate use of fluoroquinolone antibiotics… Levaquin as part of the important fluoroquinolone class of anti-ineffective prescription medications and its safety profile remains well known and established.”

As a part of the new directive from the Food and Drug Administration, officials are urging patients to tell their doctor immediately of any symptom involving tendon or nerve damage. Patients should expect to feel hallucinations, confusion, tendon or joint pain, muscle pain, pricking or tingling sensations in the feet or hands.

Cipro Lawsuits

  • Product Liability MDL Lawsuit Case Now Forming Ten Bellwether TrialsMarch 2017 – Drugmakers are facing product liability lawsuits from plaintiffs who filed cases in the US district court for the District of Minnesota. The plaintiffs are alleging that fluoroquinolone class drugs including Levaquin, Cipro, Avelox and their generic version are causing peripheral neuropathy. The judge in the case has decided to hear ten bellwether cases to help resolve more than 735 lawsuits that are pending in federal court as a fluoroquinolone multidistrict litigation (case 2642).
  • $74 Million Bayer Cipro Settlement Resolves Major Class Action SuitJanuary 2014 – Final approval to settling a class action lawsuit has been granted by a California Superior Court judge. The case alleged that Bayer, Inc. conspired with other pharmaceutical companies to keep the cost of antibiotic generic drugs from competing against brand-name pharmaceuticals. They have denied any wrongdoing that it either breached or violated state and federal regulations and laws. Even so, the Company has agreed to a $74 million settlement to pay compensatory damages to all plaintiffs involved in the class action case.
  • Using Cipro Might Be Linked to Stevens-Johnson SyndromeJune 2016 – Patients who have been prescribed Cipro (ciprofloxacin) may be experiencing the first indicators of a potentially fatal reaction to the medication. The Cipro rash has long been associated with various medications including fluoroquinolone antibiotics. The Food and Drug Administration has required the drug makers to include information on their Black Box Warning labels to immediately discontinue Cipro and other fluoroquinolone medications at the first sign of a skin rash.This is because the medication can easily cause Stevens-Johnson syndrome, where the body reacts by causing itching, fever, and inflamed pharynx. Over time, the rash can blister and detach from the skin’s outer layers. In some cases, Stevens-Johnson syndrome can exacerbate and evolve into a TEN (toxic epidermal necrolysis) condition that becomes life-threatening.

We Are Not Accepting Cipro Injury Monetary Compensation Cases

The Cipro injury case attorneys at the Drug Law Center are currently investigating, evaluating, and accepting lawsuit cases involving the popular antibiotic medication after it has caused dangerous nerve damage. We represent individuals who have been diagnosed with aortic distension, nerve damage, tendon pain, and aortic aneurysms and those who lost a loved one from a fatal injury caused by Cipro (ciprofloxacin).

If your doctor has diagnosed you with painful nerve damage, ruptured aorta, aortic tear, or another severe injury after you took Cipro, contact us today to obtain legal counsel. Let us begin the process of filing and resolving your lawsuit with a free, no obligation case evaluation to ensure your family receives a financial compensation they deserve.

To minimize your financial burden through the process of resolving your case, our law firm is currently postponing payment of all legal services. This means no upfront payment is required. Instead, we will receive payment only after we have successfully resolved your case through a negotiated settlement or through a jury award at the conclusion of your lawsuit trial.

Sources:

https://www.ncbi.nlm.nih.gov/pubmed/26436523

https://www.fda.gov/Drugs/DrugSafety/ucm500143.htm

https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm513183.htm

http://www.mayoclinic.org/drugs-supplements/ciprofloxacin-oral-route/proper-use/drg-20072288

http://www.mayoclinic.org/drugs-supplements/ciprofloxacin-oral-route/description/drg-20072288