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Crestor

The Crestor injury case attorneys at the Drug Law Center have represented many clients who have suffered serious injuries and adverse effects while taking the cholesterol medication.

Introduction

Crestor Drug RecallCrestor (rosuvastatin) is a statin (HMG-CoA reductase inhibitor) medication that has been proven effective at reducing LDL (bad) cholesterol levels and triglycerides in the bloodstream. In addition, Crestor is known to be effective at increasing the levels of HDL (good) cholesterol. To be effective at preventing cardiovascular disease, the drug is to be used concomitantly with a weight loss, diet, and exercise regimen. It is estimated that more than 11 million Americans take anti-cholesterol medications every year, including Crestor.

The History of Crestor

The Japanese pharmaceutical company Shionogi & Company developed rosuvastatin that is now marketed as Crestor, the fourth highest selling medication in America. The medical drug generates more than $5 billion in sales every year and has been approved as an effective treatment of dyslipidemia, the eight normal levels of lipids (cholesterol, triglycerides and/or fat phospholipids) in the bloodstream.

AstraZeneca holds the registered trademark on Crestor and manufactures the product that is still licensed by Shionogi & Company. The cholesterol reducing medication was approved by the U.S. Food and Drug Administration in August 2003 after more than 2400 patients suffering from hypercholesterolemia participated in clinical trials. During the study, participants had their blood LDL cholesterol levels reduced significantly when taking rosuvastatin, at a rate of 12 percent to 18 percent more than simvastatin, 26 percent more than pravastatin, 8.2 percent more than atorvastatin.

Crestor Side Effects

Like most prescription medications, Crestor has serious side effects and adverse reactions that every patient must watch for when taking the drug. Makers of Crestor and doctors recommend you stop taking the medication and seek medical attention if you experience weakness, tenderness, unexplained muscle pain, memory problems, confusion, dark-colored urine, unusual tiredness, fever, frequent urination, infrequent urination, not urinating, unexpected weight gain or swelling when taking the medication.

The most common side effects occurring when taking Crestor (rosuvastatin) include:

  • Weakness
  • Abdominal pain
  • Pains and muscle aches
  • Headaches
  • Confusion
  • Memory loss

The makers of Crestor state that serious Crestor -related muscle problems can become worse if:

  • The patient is 65 years or older
  • The patient is currently taking other drugs including Crestor
  • The patient suffers kidney problems
  • The patient suffers from hypothyroidism that has yet to be controlled
  • The patient is taking too high a dose of Crestor

Crestor Contraindication

Like every medication, Crestor has contraindications, where certain individuals should not take the medicine if they are experiencing a reaction or suffering from some medical condition that could include:

  • Blood in the urine
  • Metabolic Syndrome X
  • Liver problems
  • Liver failure
  • Blood bleeding-related stroke
  • Severe renal impairment
  • Memory loss
  • Recent surgical operation
  • Kidney failure that is caused by serious muscle damage
  • Abnormal liver function tests
  • Elevated urine proteins
  • High blood sugar
  • Tender or painful muscles with increased creatinine kinase
  • Breastfeeding or milk producing women
  • During pregnancy
  • Suffering injury

Known Problems before FDA Approval

Crestor is a popular medication that is often prescribed by doctors as an effective treatment to diminish the risk of stroke and heart attacks. However, many individuals who have been taking the cholesterol drug Crestor have suffered injuries and filed lawsuits because the drug caused Type II diabetes or liver damage.

In October 2004 report by Public Citizen revealed that 29 patients who had been prescribed Crestor unexpectedly developed kidney damage. At that time, Public Citizen stated that Crestor had a 70 times higher rate of reported kidney problems compared to all other medications in the identical class combined. The report identified a correlation between taking the medication and rhabdomyolysis, a rare disease that destroys the body’s muscle.

By the time the Food and Drug administration approved Crestor in August 2003, there had already been numerous safety concerns the delayed the approval process. Seven cases used in the clinical trials for FDA approval resulted in the development of rhabdomyolysis. The study showed a correlation of kidney abnormalities when using Crestor, that had not been revealed to had occurred when taking other statins. Even so, the FDA approved Crestor. However, the medication was to be prescribed by doctors at lower dosages that supposedly were safer.

Study results revealed that there were certain chronic bleeding conditions that patients were developing when taking Crestor. Some of these individuals needed to stop taking the medication as a result. In addition, other suffered acute kidney failure where corrective steps in dosing had to be executed to minimize the potential risk of dying. These steps included removing the kidney and other radical steps including kidney dialysis therapy.

Crestor Lawsuits

  • Development of Type II Diabetes by Statins an All Too Common Occurrence

March 2014 – Research findings from the Imperial College National Heart and Lung Institute London) indicate that Crestor, Lipitor, and other drugs used to treat cholesterol actually increased the potential risk of developing Type II diabetes in some patients who were prescribed the drug instead of controlling their cholesterol levels. The study indicated that in 20 percent of all cases patients developed Type II diabetes that likely was the result of taking the anti-cholesterol drug.

The study involved 46,000 subjects in 14 prevention trials who were given a statin medication or placebo. The study results were troubling to medical experts because of the overwhelming consensus of an already known correlation between Type II diabetes and taking statin medications. The results of these studies will likely end with hundreds of Crestor lawsuits filed by diabetic patients to hold the drug maker accountable for their failure to warn all consumers, doctors, and patients of the known potential risk of taking the defective drug.

  • Combining Antibiotics for Statins Deemed to Be Dangerous

Millions of Americans take generic and brand name anti-cholesterol statin medications to control their cholesterol and triglyceride levels. However, research now indicates that combining statins with an antibiotic could produce dangerous consequences to the body’s kidneys. The recent West University in London research results indicated that there was an obvious connection between serious adverse events and the combination of taking statins with antibiotics.

The study involved the three most popular anti-cholesterol statins including Pravachol, Lescol, and Crestor. Thirty-day outcomes were assessed from the time the patient began taking the antibiotic. The results found a consistent frequency of unfavorable events. These include hyperkalemia (dangerously high levels of blood-based potassium), kidney injuries, or rhabdomyolysis (potentially harmful breakdown of muscle tissue that can cause significant harm to the body’s kidneys).

The Foundation of a Successful Crestor Lawsuit

There are a growing number of Crestor lawsuits being filed in America by injured patients against AstraZeneca, the maker and marketer of the cholesterol-lowering medication. Many plaintiffs are alleging that the pharmaceutical giant failed to adequately warn the public, doctors, and patients of known research studies concerning dangers of the medication and the potential risk of developing diabetes after taking the drug.

Many of these plaintiffs claim that had AstraZeneca provided adequate information they would likely avoided taking this drug and instead would have chosen other options for treatment. In addition, many doctors prescribing Crestor have said they were kept in the dark and had they been provided more accurate information on the potential risks and dangers of prescribing medication they would have chosen to closely monitor their patients’ glucose (blood sugar) levels during treatment.

Many complaints filed by plaintiffs in their Crestor lawsuits allege that the drug manufacturer was negligent in their actions. Their complaints include:

  • AstraZeneca was aware, or should have been aware, of the potential risk of developing diabetes when taking Crestor, but instead chose to conceal their much-guarded information from the medical community, doctors, and patients.
  • Neither the prescribing doctor nor the patient would have had any way to know about the potential possibility of developing a serious condition when taking Crestor unless the drug maker AstraZeneca provided adequate warnings.
  • For years, the pharmaceutical company chose to ignore all the available research, data, and information about the potential risk of developing diabetes when taking the drug.

Had the drug maker or the FDA initiated a Crestor recall and provided additional warnings to consumers and the medical community, many of the plaintiffs would have never developed diabetes, suffered kidney injuries, or had the need to file a lawsuit seeking monetary recovery. This is because many Crestor-caused long-term and permanent physical damage to patient health that can diminish the quality of their life or cause their premature death.

Evaluating Potential Compensation Claim

Patients to suffer injury after taking a statin (cholesterol-lowering) medication are often challenged on what to do to determine if they have a valid legal claim against the drug maker. Generally, the patient will be required to prove three elements of their case to ensure a successful conclusion to their lawsuit. These include:

  • The patient suffered injury after taking the medication,
  • The cholesterol-lowering drug caused unreasonably serious side effects, or, the drug maker, physician, pharmacist, or others failed to provide adequate warnings of the dangers of using the drug or instructions on how to take the statin properly, and
  • There is a direct correlation to the patient’s injury and the use of the statin.

Before we accept the case, our attorneys review the evidence involving statin use and the outcome of the patient’s health before proceeding with a product liability lawsuit or claim for compensation. The complexity of these cases often makes it difficult for the patient to push back against the pharmaceutical company that will fight aggressively to suggest that they did provide sufficient warnings.

Additionally, the Crestor injury lawyer will determine the length of time the case can be filed in state or federal court based on the statute of limitations, which is the restricted time in which an injured party can seek financial recompense from all parties responsible for causing them harm.

We Are Currently Accepting Crestor Lawsuit Cases

The Crestor injury attorneys at the Drug Law Center are currently reviewing, investigating, and accepting potential compensation claims and lawsuits from individuals who became diabetic after taking the drug. If you suffered serious injuries by Crestor side effects or lost a loved one through a wrongful death after they took the cholesterol drug, you are likely entitled to file a defective product compensation claim.

You should act quickly and contact us today for a free, initial case review. We are ready to help and can evaluate your claim to make sure the statute of limitations concerning your case has not yet expired. To ensure a successful resolution to your compensation claim, we are currently accepting all Crestor lawsuits on contingency. This means we postpone payment of our fees for legal services until we successfully resolve your case through a negotiated out a court settlement or jury trial award. Our “No Win/No Fee” Guarantee ensures that you will owe is nothing if we do not win.

Sources:
http://www.mayoclinic.org/drugs-supplements/rosuvastatin-oral-route/description/drg-20065889
https://my.clevelandclinic.org/health/articles/about-cholesterol-lowering-drugs
https://www.fda.gov/newsevents/newsroom/pressannouncements/ucm498373.htm
https://www.fda.gov/Drugs/DrugSafety/ucm109095.htm

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