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Cymbalta

The Cymbalta injury case attorneys at the Drug Law Center have successfully resolved many anti-depressant financial recovery lawsuits for our clients who suffered serious withdrawal side effects while they were attempting to stop taking the drug.

History of Cymbalta

Cymbalta Drug RecallCymbalta (duloxetine) was first approved by the Food and Drug Administration (FDA) in 2004 under its generic name duloxetine for the treatment of general anxiety and depression. The medication is a class SNRI (Serotonin and Norepinephrine Reuptake Inhibitor) that doctors often prescribe as a treatment for pain caused by fibromyalgia and diabetic neuropathy.

Within months, Eli Lilly and Company began marketing Cymbalta as the only approved medication in America to manage pain caused by diabetic peripheral neuropathy. By 2006, the Food and Drug Administration issued an alert to patients being treated with antidepressants. The FDA warning instructed patients and doctors to closely observe for suicidality (suicidal thinking and behavior) when the patient initially started taking the medication. Doctors were informed to modify dosage if necessary.

Specific warnings were made for pediatric and adult patients individually. The FDA warned doctors and patients that suicidal thinking and behavior is thought to become heightened in pediatric patients on antidepressants, especially during the initial stages of treatment. It is important to note that Cymbalta had not received approval by the FDA for use in pediatric patients.

The FDA also issued warnings for adults taking antidepressant drugs including Cymbalta due to an increased potential risk of suicidal behavior. The FDA gather this information from Cymbalta controlled studies in adult women being treated for SUI (stress urinary incontinence. The results indicated a higher-than-expected rate of suicide attempts.

Three years later in February 2007, the FDA approved Cymbalta to treat generalized anxiety. The Food and Drug Administration approved Cymbalta for the maintenance of major depressive disorder in November 2007, followed by approval to manage fibromyalgia in June 2008. By 2010, the FDA cleared the way so Cymbalta could be prescribed to treat chronic musculoskeletal pain.

Cymbalta Side Effects

Doctors prescribe Cymbalta to treat a variety of conditions including anxiety disorder, depression, and pain related to fibromyalgia and diabetic peripheral neuropathy. However, like many prescription and over-the-counter medications, there are specific side effects related to taking Cymbalta. Mild side effects include:

  • Nausea
  • Constipation
  • Diarrhea
  • Dry mouth (xerostomia)
  • Tired feeling
  • Fatigue
  • Wanting to throw up
  • Difficulty in sleeping (hypersomnia)
  • Drowsiness or dizziness
  • Loss of appetite
  • Infrequent or incomplete bowel movements
  • Cymbalta Contraindications
  • Physical weakness (asthenia)
  • Sedation

More serious side effects include:

  • Agitation
  • Tension
  • Psychomotor agitation
  • Nervousness
  • Erectile dysfunction
  • Anorexia
  • Abdominal pain
  • Restlessness
  • Reduced or lost libido
  • Abdominal pain
  • Vomiting
  • Diminished appetite
  • Excessive perspiration (hyperhidrosis)

In addition to the expected side effects from taking Cymbalta, there are other major side effects that often require immediate medical attention. Most of these occur days, weeks, or years after taking duloxetine, the active ingredient in Cymbalta. Major Cymbalta side effects include:

  • Stomach or abdominal pain
  • Confusion
  • Cold sweats
  • Clay-colored stools
  • Increased thirst
  • Swelling of the eyelids, tongue, lips, face or eyes
  • Overall weakness or general tiredness
  • Yellow skin or eyes
  • Unpleasant breath odor
  • Tearing
  • Muscle or joint pain
  • Difficulty in swallowing
  • Eye pain
  • Irregular or fast heart rate
  • Decreased vision
  • Loosening, peeling or blistering of the skin
  • Decreased urine output
  • Dark urine
  • Red skin lesions with or without a purple center
  • Tightness in the chest
  • Skin rash, itching, welts and hives

Cymbalta Contraindications

Like all medications, Cymbalta has specific contraindications, where a physical condition, medical health, or use of other medications could cause significant problems when taking the anti-depression drug. Common contraindications that would lead a patient not to take Cymbalta include:

  • Serotonin syndrome – adverse medication interaction
  • High blood sugar
  • Inability to empty bladder
  • Liver problems
  • Hepatitis
  • Hardening of the liver
  • Chronic liver inflammation
  • Alcohol-related liver hardening
  • Drop in blood pressure when standing
  • Yellowing of the eyes or skin from liver problems
  • Too much alcohol consumption
  • Suicidal ideation (thinking of suicide)
  • Manic-depression
  • Mild forms of media
  • Excessive activity or cheerfulness behaviors
  • Increased potential for bleeding
  • Blood-related low-sodium amounts
  • Antidiuretic hormone secretion syndrome
  • The inability to empty the bladder
  • Narrow iridocorneal angle
  • A third-trimester pregnancy
  • Gastrointestinal motility disorder
  • A change in smoking habits
  • Elderly patients
  • When Cymbalta is used cocommitantly with CNS depressants

First Cymbalta Class Action Lawsuit

In 2012, Eli Lilly and Company, the manufacturer and marketer of Cymbalta was facing its first case filed in Federal District Court over withdrawal reactions when patients stopped taking the antidepressant medication. The case was initially filed at the end of October 2012 and was amended in federal court on the first day of 2013 as a Class Action lawsuit. Plaintiffs in the case involved consumers from Missouri, Massachusetts, California, and New York.

Lawsuit documents revealed that plaintiffs were alleging that Lily and Company had omitted crucial information concerning withdrawal factors through their marketing and labeling materials. Because of that, the plaintiffs were claiming that consumers were never given a real opportunity to make an actual informed decision about whether to take the medication or choose other options.

Nationwide lawsuits were being filed at approximately the same time including set Cymbalta lawsuits involving withdrawal reactions filed by plaintiffs in Pennsylvania, New York, California, and Arizona. The following year in 2014, many more Cymbalta lawsuits were filed, this time in Wisconsin, Pennsylvania, North Carolina, Oregon, Minnesota, Ohio, Louisiana, Maryland, Georgia, Florida, and California. Many individuals were coming forward to hold Eli Lilly and Company financially and morally responsible for the defective design of their antidepressant medication.

Cymbalta Lawsuits

Many individuals are filing Cymbalta lawsuits to recover financial compensation for the damages the antidepressant medication has caused them. Some of these class-action cases and individual lawsuits include:

  • Florida Woman Files Cymbalta Withdrawal Injury Losses

Eli Lilly and Company is facing one more Cymbalta withdrawal lawsuit, this time filed by a Florida woman who alleged the drug maker failed to provide adequate instructions on how to appropriately take the antidepressant. In addition, the plaintiff is claiming that the popular medication was defective because she had no way to gradually reduce the amount of drug dosage she was taking to ensure her safety.

Lawsuit documents revealed that in 2010, the plaintiff was prescribed Cymbalta to treat migraines. The Florida woman made the decision to stop using the antidepressant medication because she felt it was inefficient at treating the migraines. However, she claims she suffered serious Cymbalta withdrawal symptoms during her attempt to reduce the dosage intake of the drug. The plaintiff claims she suffered blurry vision, headaches, memory loss, vomiting, hot and cold flashes along with anxiety during her withdrawal.

Lawyers building the Florida woman’s withdrawal lawsuit case documented that the drug maker “should have been aware of the significance of the antidepressant withdrawal.” Her attorneys are claiming that Eli Lilly and Company conducted their own studies on the withdrawal process and the problems it produced.

  • Florida Couple File Cymbalta Withdrawal Symptoms against Eli Lilly & Company

A Tampa couple has filed an antidepressant Cymbalta withdrawal lawsuit in federal court alleging the pharmaceutical giant failed to warn the wife about the potential side effects that can occur when she stopped taking her medication. The lawsuit was filed four years after the plaintiff was first prescribed Cymbalta back in 2011. Her doctors recommended using the drug to treat her fibromyalgia and osteoarthritis pain symptoms. Unfortunately, the drug proved to be an effective at relieving pain.

Lawsuit documents reveal that the plaintiff was concerned about suffering potential long-term side effects of taking the antidepressant drug and instead chose to wean off the medication while under the care and supervision of her physician. However, she began experiencing dangerous and severe withdrawal symptoms that included depression, nightmares, dizziness, nausea, and personality changes.

The plaintiff is claiming that Eli Lilly and Company failed to adequately warn her, her doctor in the medical community about the potential risks. Many other plaintiffs with the same allegations of been consolidated in a Cymbalta Class Action lawsuit. Even though clinical trials conducted by Lily concluded that there was a 9.6 percent to 17.2 percent chance that users of Cymbalta will suffer severe withdrawal symptoms. The Florida woman’s attorneys are saying that she became a prisoner to both Lily and Cymbalta financially because she was physically dependent on taking the drug long-term.

  • Lawsuit Alleges Stevens-Johnson Syndrome Was Caused by Taking Cymbalta

Eli Lilly and Company is facing one more antidepressant Cymbalta lawsuit, this time filed by an Arkansas woman who alleges that taking the drug led to the development of Stevens-Johnson syndrome (SJS) an often life-threatening skin disease that causes burn-like rashes. The plaintiff is alleging that Lily failed to adequately warn her of the potentially fatal, dangerous side effects the drug produces.

Lawsuit documents reveal that in 2012, the plaintiff’s doctors prescribe Cymbalta. By the end of the year, her doctors had increased her dosage. That is when she started manifesting common symptoms of Stevens-Johnson syndrome including peeling skin, sores, and rashes. Her right foot, mouth, and tongue also became blistered. It was then that she sought medical treatment where physicians diagnosed her with Stevens-Johnson syndrome thought to be caused by a Cymbalta adverse reaction.

The plaintiff is making claims that the reaction and side effects he experienced lead to damage of her nervous system and caused severe injury to her right leg that included “complex regional pain syndrome.” Her attorneys are alleging that these injuries are causing permanent chronic serious pain and that Lily ignored a directive from the U.S. FDA (Food and Drug Administration) to investigate the correlation between developing SJS and taking Cymbalta.

FDA Report Warns of Cymbalta Withdrawal Problems

In 2009, the Food and Drug Administration started receiving reports listing common Cymbalta side effects. This led to a plan to study these issues to develop effective protocols in helping patients withdraw from the antidepressant medication.

Documents by the FDA revealed that there are two specific Cymbalta side effect categories that many patients experience when they cease taking the medication. This includes physical effects like changes in mood, neurological problems, and painful physical issues. However, the FDA also notes professional and social effects that occur from problems that arise with taking Cymbalta. This includes irritability, anger, and extreme mood swing behaviors.

Now Accepting Cymbalta Lawsuits on Contingency

The Cymbalta injury case attorneys at the Drug Law Center are now accepting antidepressant financial recovery lawsuits from patients who have suffered harm caused by taking or ceasing to take the antidepressant medication. If you have suffered injury or lost a loved one after they took Cymbalta, do not hesitate to contact our law offices today. We have successfully resolved many antidepressant lawsuits because we fight aggressively against pharmaceutical companies that are eager to place blame on the victimized patient.

We offer our clients a complimentary, lawsuit evaluation to discuss the merits of their case to provide numerous legal options on how to proceed. We are currently postponing payment of our legal services in all Cymbalta lawsuits and offer every client a “No Win/No Pay” guarantee. This means you owe us nothing if we are unable to secure an acceptable out of court settlement or win your case at trial.

Sources:
http://www.clevelandclinicmeded.com/medicalpubs/pharmacy/septoct2004/duloxetine.htm
https://www.fda.gov/Drugs/DrugSafety/ucm114966.htm
https://www.accessdata.fda.gov/drugsatfda_docs/nda/2004/021427_s000_Cymbalta.cfm
https://www.fda.gov/downloads/advisor…/ucm172866.pdf
http://www.mayoclinic.org/drugs-supplements/duloxetine-oral-route/description/drg-20067247