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The Eliquis injury attorneys at the Drug Law Center are currently conducting an investigation into our clients’ injuries that were caused by the blood thinning medication.
Eliquis (apixaban) is a popular anticoagulant (blood thinner) used to treat systemic embolism and venous thromboembolism events including DVTs (deep vein thrombosis). As a direct factor-Xa monitor, the drug has the ability to lower the potential risk of recurrent pulmonary embolism or DVT. However, the blood thinning medication is known to cause bleeding that has the potential to lead to death because it can block certain clotting substance activities in the bloodstream. Many patients take the anticoagulant to lower the potential risk of developing a blood clot-related stroke, especially those suffering from atrial fibrillation or other heart rhythm disorder. Individuals with an artificial heart valve should avoid taking Eliquis as should individuals who have active bleeding caused by an injury or surgery. However, to avoid a sudden increase in the potential development of a stroke or blood clot, it is important to never stop taking the medication unless instructed by your doctor.
The History of Eliquis
The generic form of Eliquis, apixaban, in tablet form was first approved in Europe in 2012 and then later approved under the brand name Eliquis by the Food and Drug Administration in December of that year. The approval of the Bristol-Myers Squibb Company and Pfizer Inc. manufactured product a doctor to prescribe the medication as a treatment for preventing thromboembolism in atrial fibrillation and as a deep vein thrombosis prophylaxis after hip or knee replacement surgery.
Over the years, the two pharmaceutical companies have marketed Eliquis as being more effective than warfarin in reducing the “risk of developing a stroke” and that the medication causes “significantly less major bleeding than warfarin” as found in the clinical trial. The company suggested that medication is highly effective in treating atrial fibrillation, a certain kind of irregular heartbeat that affects more than 3 million men and women in the United States.
Research indicates that individuals suffering from atrial fibrillation have a five times greater chance of suffering from a stroke compared to those without the condition. Clinical trials show that individuals taking Eliquis to times a day suffered 21 percent fewer strokes compared to individuals on warfarin, a competitive blood thinning medication. However, no agent is available to rapidly reverse the effects of Eliquis and preventing clotting, meaning that the patient could suffer serious blood loss and potentially die if any external or internal bleeding cannot be controlled.
Eliquis Side Effects
Eliquis packaging contains an FDA approved “Black Box Warning” that reveals the product can cause an increased potential risk of stroke in individual suffering with atrial fibrillation, especially when the patient stopped taking the drug. An additional black box warning reveals that taking the medication can cause a severe blood clot around the spinal column after the patient receives spinal anesthesia, a spinal puncture, or epidural. In some cases, the blood clot causes permanent or long-term paralysis. Individuals with a history of spinal surgeries, spinal deformity, spinal punctures or epidural catheter should discuss their medical history with their doctor.
There are numerous Eliquis side effects that affect each individual patient differently in its severity and likelihood. The most common side effects of taking Eliquis (apixaban) include:
- Rectal bleeding
- Cerebral hemorrhaging
- Easy bruising
- Coughing blood
- Bleeding from an open wound
- Operation-related bleeding
- Bleeding in the abdomen
- Bleeding from the intestines or stomach
- Blood or bruising around the eye or eyelid
- Brain bleeding-related stroke
- Spinal epidural hematoma
- Bowel movement-related red blood
- Potentially fatal allergic reaction
- Decreased blood platelet levels
- Blood in the urine
- Skin rash, hives, or itching
- Vomiting, nosebleeds, or nausea
- Unexpected weakness or tiredness
- The sensation of chest tightening
- Shortness of breath
- Difficulty swallowing
- Fast heart rate
- Edema (swelling)
- Joint pain
- Water retention
- Unexplained bleeding not associated with menstrual cycle
- Blood hemorrhaging below the skin
- Conjunctivitis-associated eye hemorrhaging
- Feeling faint
- Black tarry stools
A Link between Eliquis and Hemorrhagic Shock
Excessive bleeding can cause an individual to experience hemorrhagic (hypovolemic) shock as a side effect that happens when 20 percent or more of the body’s blood has bled out from the bloodstream. In many cases, the blood loss is not obvious as it leaks from one or more organs to the point where it can no longer function.
When shock occurs, certain areas of the body have insufficient levels of blood, tissues and organs are deprived of nutrients and oxygen needed to survive. One by one, the organs can begin to shut down causing shock symptoms to occur. Usually, there is a sudden drop in blood pressure and body temperature is vital organs are cut off from blood flow circulation.
Often, blood thinning medications cause potentially life-threatening complications when we started as a simple bleed inside the body continues to the point that causes kidney damage, brain damage, heart attack, stroke, organ damage, gangrene and eventually death, if the bleeding cannot be detected or stopped.
Eliquis label warnings reveal known specific interactions with the brand-name and generic form apixaban when used with other dietary drugs, nutritional supplements, herbal remedies, nonprescription medications, and all other prescriptions. Serious interactions with Eliquis for the generic version include:
- Dilantin or Phenytoin (Phenytek)
- Teril, Tegretol, Equetro, Epitol, or Carbatrol
- Kaletra (rutibaur) or Norvir
- Rifater (rifampin), Rigadin, Rimactane, or Rifadin
- SNRI (serotonin norepinephrine reuptake inhibitor) like Cymbalta, Pristiq, Fetzima, Khedezla, Effexor or Savella
- Sporanox (itraconazole) or Onmel
- Prevpac (clarithromycin) or Biaxin
- Nizoral (ketoconazole)
Overdosing on Eliquis or apixaban could cause significant side effects that include unexpected bruising or unusual bleeding, along with red, pink, or brown urine, coughing up material or blood appearing like coffee grounds, or red or black tarry stools.
Monitoring Coagulation and Anti-Coagulation
Even though millions of patients are prescribed Eliquis and other anticoagulant medications every year, few doctors perform coagulation and anti-coagulation monitoring to measure the concentration of the drug or its activity in the body. However, because the medication is a direct factor-Xa inhibitor, because of the potential bleeding complications, understanding and assessing the concentration levels of the drug could be extremely useful in some cases.
Every anticoagulant medication varies on its effectiveness. In some cases, it might be imperative for the doctor to understand the concentrated levels of the medication that may require a dosage adjustment to control bleeding disorders or thrombophilia.
New advancements in anticoagulant medications have increased competition in the U.S. medical marketplace since the Food and Drug administration approved new anticoagulant drugs. These new meds promise patients will enjoy superior benefits over older products like warfarin when requiring blood thinners to maintain their health.
The recent approval of Eliquis, Pradaxa, and Xarelto has changed the way that people take blood thinning medications. Unfortunately, no approved antidote, like those available with warfarin, have been approved for these new drugs. Having an antidote is important because the medication is designed to minimize the potential of developing blood clots by causing anticoagulation and bleeding sites.
Many losses have been file my personal injury attorneys specialize in medical malpractice product liability cases. These attorneys represent plaintiffs who alleged that the drug manufacturer failed to warn them, their doctors and the public of the potential risk and severe injuries that can occur when using Eliquis, apixaban, and other anticoagulant drugs.
By 2014, plaintiffs had filed more than 4000 Pradaxa lawsuits. Many of these original claims for compensation were settled out of court on an average of $150,000 each and totaling more than $650 million. Two years later in 2016, additional plaintiffs filed another 3000 Eliquis lawsuits that have since been centralized in federal court in Louisiana.
- Eliquis Group Lawsuit Filed by Plaintiffs Suffering Dangerous Side Effects Including Life-Threatening Bleeding
Pfizer Inc., Bristol-Myers Squibb Company, and McKesson Corporation are all facing an Eliquis group lawsuit filed by plaintiffs alleging the injuries they suffered are directly correlated with taking Eliquis, a popular blood thinner medication. As a part of the group lawsuit, one plaintiff has filed suit on behalf of their deceased mother claiming that Eliquis side effects were directly responsible for causing the wrongful death of the plaintiff’s mother due to uncontrollable gastrointestinal and rectal bleeding.
Another plaintiff has filed a lawsuit against the pharmaceutical giants claiming a wrongful death of her deceased husband after he died from gastrointestinal bleeding complications. A third plaintiff filed her Eliquis lawsuit claiming she developed excessive bleeding requiring hospitalization on numerous occasions. A fourth plaintiff claims that the anticoagulant medication cost bleeding in his urine and stool. His condition degraded to the point where excessive bleeding led to a stroke.
More plaintiffs joined in the Eliquis injury lawsuit where excessive bleeding led to seven different hospitalization visits before surgery was able to correct the bleeding condition. Finally, two other plaintiffs filed lawsuits on behalf of the estates of their deceased loved ones one who died from gastrointestinal bleeding complications and the other acute cranial hemorrhaging, allegedly both brought on by using the blood-thinning Eliquis medication. These losses are a small sample of the eloquence group lawsuit that has been filed in the Superior Court of the state of California, in the County of Los Angeles.
Let’s Start Your Eliquis Lawsuit Today
Did you or a loved one suffer a bleeding injury from an anticoagulant (blood thinning) medication? The Eliquis injury attorneys at the Drug Law Center are here to help. Our law firm is currently accepting uncontrollable bleeding injury lawsuits that involve hemorrhaging, product liability, stroke, heart conditions, and wrongful death.
We build successful cases to obtain financial compensation by proving the correlation between taking brand-name Eliquis in its generic form apixaban and severe internal bleeding complications that often prove to be fatal.
Our team of dedicated personal injury attorneys will fight aggressively on your behalf against the manufacturers of Eliquis, Xarelto, and Pradaxa. These drug makers promote their medications as superior alternatives to older blood thinners like Coumadin (warfarin). We represent clients in individual Eliquis cases and those involved in multidistrict litigation (MDL) in centralized locations including the Eastern District of Louisiana and the more than 50 cases that have already been filed and centralized as an MDL case in the US District Court for the Southern District of New York.
Contact us today so we can begin resolving your Eliquis lawsuit through a complimentary, full case evaluation with one of our experienced blood thinning injury attorneys. Our law firm offers a “no win/no fee” guarantee. This means you will not pay us for our legal services until after we have successfully resolved your case by negotiating a settlement on your behalf outside of court or by winning your case at trial.